Do PPIs inhibit the gut microbiome?
Do PPIs inhibit the gut microbiome? Physicians widely prescribe proton pump inhibitors (PPIs) to treat and prevent symptoms associated with gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs inhibit gastric acid secretion, resulting in reduced acid in the stomach (hypochlorhydria). While low acid provides an opportunity for injured mucosa in the upper GI tract [...]